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Want to get to pathogenic genomic insights?

With Bionano optical genome mapping (OGM) you can finally detect previously unseen, pathogenic variants, in hematological malignancies.

OGM is the breakthrough you’ve been waiting to see

In a single assay, the OGM Saphyr ®  system can detect all classes of chromosomal aberrations in hematological malignancies, revealing critical structural variants (SVs) hidden in the genome that have never been seen before.

• Accurately identify all classes of SVs

• 500 base pair resolution

• 5% variant allele frequency

• 10,000x more resolution than karyotyping, less subjective results

OGM is high-resolution

The genome-wide OGM platform uses unbiased, digital precision to reveal the pathogenic structural variants that can increase the number of resolved hematological malignancy samples, and better stratify risk profiles. No more having to sign off on sample reports as “no genetic determinant identified” because the technology wasn’t there to reveal the pathogenic cytogenetic variants.

OGM fits your lab

The Saphyr ®  system consolidates multiple technologies into one to create a single, simple, OGM sample-to-answer workflow. Now there is a single method for studying all structural and numerical variant classes. The Saphyr ®  system is a streamlined workflow, easy to implement, with no need for cell culture or complex and subjective microscope analysis, system.

OGM reliability is real

Join the growing community of cytogeneticists, pathologists and hematopathologists who are embracing OGM to maximize their number of relevant cases and uncover new ways forward to seeing variants of biological significance.

Optical Genome Mapping as a Perfect Technique for Interrogating Structural Variants