T-cell Services
Monitor T-cell activation. Characterize cellular immune responses. Identify coincident B- and T-cell epitopes.
New analytical services with cell-based functional assays.
Monitor T-cell activation. Characterize cellular immune responses. Identify coincident B- and T-cell epitopes.
New analytical services with cell-based functional assays.
Map T-cell epitopes and monitor cellular immune responses.
The activation of T-cells is antigen-specific and requires recognition of peptides that are bound to HLA molecule (peptide-HLA) by a T-cell receptor. With ELISpot assays, you can determine the frequency of antigen-specific T-cells in your sample.
The new T-cell services in T-cell immune monitoring and epitope mapping are useful for multiple applications:
T-cell monitoring in vaccine development or after infection
Evaluating T-cell modulating effects of tolerizing peptides in autoimmune diseases
Identification of epitopes of autoreactive T-cells
Evaluating T-cell modulating effects of monoclonal antibodies in cancer therapy
Identification of T-cell epitopes for vaccines development.
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Other Resources :
Immunogenic B-cell and T-cell Epitopes
Learn how to use PEPperCHIP ®️ Peptide Microarrays combined with functional T-cell activation assays to discover coincident B- and T-cell receptor epitopes. Click here for the application note.