The XenX irradiator platform has been designed to allow high throughput targeted irradiation studies on cells and small animals. XenX is equipped with a 225 kVp X-ray tube and a 360 degree rotational gantry to allow beam delivery from any angle. Portal imaging allows for a beams eye view of the specimen, and the ability to perform a double exposure technique enables targeting of orthotopic and ectopic tumors with a collimated beam.
The XenX irradiator platform has been designed to allow high throughput targeted irradiation studies on cells and small animals. XenX is equipped with a 225 kVp X-ray tube and a 360 degree rotational gantry to allow beam delivery from any angle. Portal imaging allows for a beams eye view of the specimen, and the ability to perform a double exposure technique enables targeting of orthotopic and ectopic tumors with a collimated beam.
An upgrade from a standard, fixed source, single planar X-ray cabinet irradiator. The XenX allows investigators to deliver beams of radiation in a clinically relevant and translatable way. These techniques result in a more 3D conformal dose to the target area, while drastically minimizing normal tissue and surrounding tissue toxicity. With the ability to deliver a beam or radiation from any angle, XenX allows you to investigate and answer questions that were otherwise unattainable with a fixed beam cabinet irradiator.
XenX enables investigators from various backgrounds to perform clinically relevant research in a preclinical laboratory setting. The ability to mimic clinical radiation practice in an in vivo model allows for investigation of research end points that have not been attainable up until now. Adopting clinical techniques like imaging, target localization, and avoidance of normal tissue toxicity will only drive the field and understanding of radiation effects to the tumor forward.
Oncology
Radiobiology tumor micro-environment
DNA repair
Bystander effects
Radiosensitivity of normal tissue
Preclinical studies
Radiosensitizsers
In Vivo irradiation