Translational aspects of preclinical image-guided precision radiation studies: Maximizing clinical relevance
Interactive Webcast on Tuesday, May 31 at 5pm BST
As new technologies increase the accuracy and clinical relevance of our delivery of radiotherapy to preclinical models of cancer, it becomes even more important that the preclinical models are also representative of the clinical scenario. There are limitations to using subcutaneous xenograft models.
Join Xstrahl and Prof. Anthony Chalmers, Chair of Clinical Oncology at the University of Glasgow, as he describes the value of using orthotopic models of cancer in preclinical irradiation experiments.
Specifically, he will address two main methods:
1) Genetically engineered mouse models (GEMM), in which the host immune system is also preserved
2) Orthotopically implanted xenografts, which generally require the use of immunocompromised host animals.
Prof. Chalmers will provide examples of how these models are being used in Glasgow to conduct clinically relevant radiotherapy research with the SARRP system. Prof. Chalmers will also be available for Q&A following the presentation.
Speaker:
Prof. Anthony Chalmers
Chair of Clinical Oncology, University of Glasgow, United Kingdom
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